Anterior Pituitary Hormone Replacement in Traumatic Brain Injury

How closely are hormone levels linked to brain injury?
And further, once adjusted,do they improve quality of life for a brain injury survivor?

Forty percent of adults who suffer a traumatic brain injury (TBI) that requires hospitalization and rehabilitation have been found to have a hormonal abnormality. Low hormone levels can cause decrease aerobic capacity, psychological changes including fatigue and diminished sense of well-being, and changes in body composition including diminished lean body mass, increased fat and decreased bone mineral density. This study is looking at thyroid, GH, and cortisol hormone levels.